Why is CankerClear™ So Effective?

Doctor Formulation

CankerClear™ is a breakthrough proprietary treatment that effectively combines the most powerful and extensively researched ingredients, giving you an all-in-one solution. Every single ingredient in CankerClear™ was hand-picked by a team of medical doctors and scientific researchers, based on clinical data and designed to treat canker sores and get results more effectively than any other canker sore treatment available.

CankerClear™ contains 7 tested ingredients that meet the strength and purity standards of the USP/NF (United States Pharmacopeia–National Formulary). Each ingredient was carefully researched and included based on clinical data. No other non-prescription solution comes close to CankerClear™ in terms of quality and purity of ingredients.

Recommended Directions: Apply a pinch of the powder on or near the inflammation or sore. Allow 60 to 100 seconds before removing powder. Your mouth will become wet with saliva. Use the saliva and powder mixture to swish thoroughly for up to three minutes. Repeat 2 - 3 times during the day. As a preventative, mix powder with water and swish in your mouth 1 - 2 times a week.

Click here to see our label.

CankerClear™ 's - Proprietary Blend of Ingredients:

    Alum (Aluminum Potassium Sulfate) has many uses as an astringent and antiseptic in various industrial, cosmetic, chemical and cooking and baking processes. It is both an acid and an astringent which is to say, a compound that causes shrinking or constricting of blood vessels and/or mucous membranes. Alum Powder is often used for extracting the water out of food (e.g. pickle making). It is suggested that it may offer similar benefits for canker sores too, by removing the moisture from the ulcer which then gives it chance to heal. It has been shown to have antiperspirant and antibacterial properties which also play a part in absorbing water.

    *References:
  1. Aguilar, T. N.; Blaug, S.M.; Zopf, L.C. (July 1956). "A study of the antibacterial activity of some complex aluminum salts". Journal of the American Pharmaceutical Association. American Pharmaceutical Association 45 (7): 498–500.PMID 13345689.
  2. Greenwood, N. N.; & Earnshaw, A. (1997). Chemistry of the Elements (2nd Edn.), Oxford: Butterworth-Heinemann. ISBN 0-7506-3365-4.
  3. Kanlayavattanakul, M.; Lourith, N. (1 August 2011). "Body malodours and their topical treatment agents". International Journal of Cosmetic Science 33 (4): 298–311. doi:10.1111/j.1468-2494.2011.00649.x. PMID 21401651
  4. Vitamin B12 is mostly known for its energy-enhancing properties and is especially important for the brain and nervous system, and its role in the production of blood. B12 deficiencies have been documented in people suffering from canker sores and studies have shown huge benefits for Vitamin B12 supplementation.

    According to results published from a study in Spring 2009, conducted at the Ben-Gurion University of the Negev in Israel, B12 demonstrated huge benefits in treating canker sores. 74% of the treated group had total remission of canker sores. Average duration and severity were also decreased and after 6 months, had almost completely gone.

    *References:
  5. Volkov et al. Effectiveness of Vitamin B12 in Treating Recurrent Aphthous Stomatitis: A Randomized, Double-Blind, Placebo-Controlled Trial. The Journal of the American Board of Family Medicine, 2009; 22 (1): 9 DOI: 10.3122/jabfm.2009.01.080113
  6. Sun A, Chen HM, Cheng SJ, Wang YP, Chang JY, Wu YC, Chiang CP. Significant association of deficiencies of hemoglobin, iron, vitamin B12, and folic acid and high homocysteine level with recurrent aphthous stomatitis. J Oral Pathol Med. 2015 Apr;44(4):300-5. doi: 10.1111/jop.12241. Epub 2014 Jul 22.
  7. Lopez-Jornet P, Camacho-Alonso F, Martos N. Hematological study of patients with aphthous stomatitis. Int J Dermatol. 2014 Feb;53(2):159-63. doi: 10.1111/j.1365-4632.2012.05751.x. Epub 2013 Jul 24.
  8. Kozlak ST, Walsh SJ, Lalla RV. Reduced dietary intake of vitamin B12 and folate in patients with recurrent aphthous stomatitis. J Oral Pathol Med. 2010 May;39(5):420-3. doi: 10.1111/j.1600-0714.2009.00867.x. Epub 2010 Feb 7.
  9. Baccaglini L, Lalla RV, Bruce AJ, Sartori-Valinotti JC, Latortue MC, Carrozzo M, Rogers RS (2011). "Urban legends: recurrent aphthous stomatitis". Oral Diseases 17 (8): 755–770. doi:10.1111/j.1601-0825.2011.01840.x. PMC 3192917. PMID 21812866.
  10. Propolis is a resinous mixture that honey bees collect from trees and plants. It has been used in traditional medicines for years and endorsed by institutes such as the National Institute of Health declaring it's "possibly effective" for treating cold sores, genital herpes, and post-surgery mouth pain. It has been shown to contain antibacterial and antifungal properties.

    Researchers at Saudi Arabia's Salman bin AbdulAziz University found that treating cankers sores with honey reduced the pain and intensity of the sore and sped up healing times.

    *References:
  11. "Propolis: MedlinePlus Supplements". U.S. National Library of Medicine. January 19, 2012.
  12. da Silva, F. B.; Almeida J. M.; Sousa S. M. (April–June 2004). "Natural medicaments in endodontics - a comparative study of the anti-inflammatory action". Braz Oral Res. 18 (2): 174–9. doi:10.1590/s1806-83242004000200015. PMID 15311323. Retrieved 2008-01-14.
  13. Samet, N.; Laurent C.; Susarla S. M.; Samet-Rubinsteen N. (June 2007). "The effect of bee propolis on recurrent aphthous stomatitis: a pilot study". Clin Oral Investig. 11 (2): 143–7. doi:10.1007/s00784-006-0090-z. PMID 17285269.
  14. Atanasovska Stojanovska A1, Popovska M, Muratovska I, Mitic K, Stefanovska E, Radojkova Nikolovska V. Therapeutic effect of proaftol in treatment of recurrent aphthous stomatitis.Prilozi. 2014;35(3):195-202.
  15. Cherniack EP. Bugs as drugs, Part 1: Insects: the "new" alternative medicine for the 21st century?Altern Med Rev. 2010 Jul;15(2):124-35.
  16. Martínez Silveira G, Gou Godoy A, Oña Torriente R, Palmer Ortiz MC, Falcón Cuéllar MA. Preliminary study of the effects of propolis in the treatment of chronic gingivitis and oral ulceration. Rev Cubana Estomatol. 1988 Sep-Dec;25(3):36-44.
  17. Licorice is the root of Glycyrrhiza glabrahas. It has been used as a healing agent for more than 4,000 years and is known for its antiviral, antimicrobial and anti-inflammatory qualities. It is thought to soothe and coat injured tissues in the mouth, to help provide quick relief for canker sores. In addition, it numbs the injured tissue and covers the sore. It also acts as a pain reducer pain and helps speed up healing. Furthermore, it offers some extra benefits such as helping to prevent tooth decay and promote general oral hygiene care.

    In one clinical trial, it was discovered that 80% of canker sore sufferers using an oral patch containing licorice root extract experienced significant pain reduction in just three days and managed to shrink the sore to one-tenth its original size after seven days. A further study found that 96% of canker sores treated with licorice root extract experienced significant healing within three days.

    *References:
  18. Borrelli F, Izzo AA. The plant kingdom as a source of anti-ulcer remedies. [Review]. Phytother Res. 2000;14(8):581-591.
  19. Fiore C, Eisenhut M, Ragazzi E, Zanchin G, Armanini D. A history of the therapeutic use of liquorice in Europe. J Ethnopharmacol. 2005;99(3):317-24.
  20. Messier C, Epifano F, Genovese S, Grenier D. Licorice and its potential beneficial effects in common oro-dental diseases. Oral Dis. 2012 Jan;18(1):32-9. doi: 10.1111/j.1601-0825.2011.01842.x. Epub 2011 Aug 18.
  21. Mekseepralard C, Kamkaen N, Wilkinson JM. Phytother Res. Antimicrobial and antioxidant activities of traditional Thai herbal remedies for aphthous ulcers. 2010 Oct;24(10):1514-9. doi: 10.1002/ptr.3158.
  22. Lysine is an amino acid which plays a major role in calcium absorption and the body's production of hormones, enzymes, and antibodies. Calcium deficiencies are thought to be present in canker sores sufferers. Therefore, lysine supplementation is thought to promote prevention of canker sores by assisting increased calcium intake.

    *References:
  23. http://umm.edu/health/medical/altmed/supplement/lysine
  24. Ogura M, Yamamoto T, Morita M, Watanabe T. A case-control study on food intake of patients with recurrent aphthous stomatitis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Jan;91(1):45-9.
  25. Wright EF. Clinical effectiveness of lysine in treating recurrent aphthous ulcers and herpes labialis. Gen Dent. 1994 Jan-Feb;42(1):40-2; quiz 51-2.
  26. Folic Acid is a B vitamin instrumental for many bodily functions. Nutritional folate deficiencies play a role in predisposing a person to canker sores. One study of people with canker sores found that over half were deficient in iron, folate, or vitamin BI2. When they supplemented their diets, almost all of them found that their canker sores disappeared. Supplementation is strongly recommended in the prevention of canker sores.

    *References:
  27. Sun A, Chen HM, Cheng SJ, Wang YP, Chang JY, Wu YC, Chiang CP. Significant association of deficiencies of hemoglobin, iron, vitamin B12, and folic acid and high homocysteine level with recurrent aphthous stomatitis. J Oral Pathol Med. 2015 Apr;44(4):300-5. doi: 10.1111/jop.12241. Epub 2014 Jul 22.
  28. Lopez-Jornet P, Camacho-Alonso F, Martos N. Hematological study of patients with aphthous stomatitis. Int J Dermatol. 2014 Feb;53(2):159-63. doi: 10.1111/j.1365-4632.2012.05751.x. Epub 2013 Jul 24.
  29. Kozlak ST, Walsh SJ, Lalla RV. Reduced dietary intake of vitamin B12 and folate in patients with recurrent aphthous stomatitis. J Oral Pathol Med. 2010 May;39(5):420-3. doi: 10.1111/j.1600-0714.2009.00867.x. Epub 2010 Feb 7.
  30. Holy Basil leaves contain essential oils that produce eugenol, methyl eugenol and caryophyllenehas which have amazing purifying and cleansing properties. Scientific studies have established that compounds in basil oil have potent antioxidant, antiviral, and antimicrobial properties, making it an effective treatment for canker sores.

    *References:
  31. Bozin B, Mimica-Dukic N, Simin N, Anackov G (March 2006). "Characterization of the volatile composition of essential oils of some lamiaceae spices and the antimicrobial and antioxidant activities of the entire oils".J. Agric. Food Chem. 54 (5): 1822–8.doi:10.1021/jf051922u. PMID 16506839.
  32. Chiang LC, Ng LT, Cheng PW, Chiang W, Lin CC (October 2005). "Antiviral activities of extracts and selected pure constituents of Ocimum basilicum". Clin. Exp. Pharmacol. Physiol. 32 (10): 811–6.doi:10.1111/j.1440-1681.2005.04270.x.PMID 16173941.
  33. de Almeida I, Alviano DS, Vieira DP et al. (July 2007). "Antigiardial activity of Ocimum basilicum essential oil". Parasitol. Res. 101 (2): 443–52.doi:10.1007/s00436-007-0502-2. PMID 17342533.